Size Exclusion Chromatography

Malvern Scientists will Lead Protein Characterization Workshop at PEGS Summit

Drs Kevin Mattison*, Ulf Nobbmann and Jason Sanchez of Malvern Instruments will lead a workshop on ‘Characterization techniques for protein therapeutics’ - at the 7th Annual PEGS - Protein & Antibody Engineering Summit being held in Boston MA, from 9-13 May 2011. As a corporate sponsor, Malvern Instruments will also be exhibiting and company experts will be on hand to discuss light scattering, size exclusion chromatography (SEC) and dynamic imaging technologies.

The workshop will cover the theory and general application of both traditional and emerging technologies suitable for protein therapeutic characterization, across the applicable size range of 1 nm to 100 µm. Participants will seek to answer questions such as: What’s the difference between Tm measured by DSC, CD, & DLS? Can DLS be used to confirm SEC results? What’s the relevance of protein charge on formulation stability? Can particle counting be achieved in the 100 nm to 1 µm size range? What role does protein aggregate “morphology” play?

Malvern solutions for characterizing proteins and other macromolecules include: the Zetasizer µV with OmniFACE and OmniSEC, a new SEC-LS detector package dedicated to protein analysis; Zetasizer Nano systems, which use dynamic and static light scattering to measure size and molecular weight; Viscotek size exclusion chromatography systems/detectors for molecular weight and molecular structure characterization; Sysmex FPIA-3000 for dynamic imaging, size and shape characterization of protein aggregates.

For details of Malvern’s protein solutions visit the company article page. 

*Kevin Mattison is Principal Scientist, Bioanalytics; Ulf Nobbmann is Senior Applications Specialist, Nanometrics; and Jason Sanchez is Product Manager GPC/SEC Technologies, all at Malvern Instruments.

Handbook of Size Exclusion Chromatography and Related Techniques ...

Gel permeation chromatography (GPC), or size exclusion chromatography (SEC), has evolved steadily since its development in the 1960s. New columns, detectors, and methodologies have been introduced at a timely pace to push the limits of technology. In the most recent Waters International GPC 2003 and ISPAC-16 Symposium (Baltimore, Maryland, June 7–12, 2003), more than 80 very interesting papers were presented by scientists from all over the world. This demonstrates that the interest in determining the molecular weight and molecular weight distribution of polymers accurately, precisely, and efficiently has remained high throughout the years. top-engineering-ebooks.blogspot.com website are for private use only. No files are hosted on our server, they are only indexed much like how Google works. This site merely indexes of other sites contents. The hosting server or the administrator cannot be held responsible for the contents of any linked sites or any link contained in a linked site, or changes / updates to such sites. All materials on this website is for Educational Purposes ONLY. Top-engineering-ebooks.blogspot.com makes no representations about the accuracy or suitability of the information or links provided on this web site. The information is provided AS IS without express or implied warranty. The use of information and links shall remain at the users risk. top-engineering-ebooks.blogspot.com takes no responsibility for the contents of this site including but not limited to and contents of Internet sites that link from the site The links are provided for public access and download. Publisher is responsible for the content of the files.Under no circumstances top-engineering-ebooks.blogspot.

Size exclusion chromatography

This book is intended for either those new to the field of SEC, or for those research workers who require a more comprehensive background.

Size exclusion chromatography

Size exclusion chromatography, methodology and characterization of polymers and related materials

Size Exclusion Chromatography

Handbook of size exclusion chromatography and related techniques

This volume presents the latest findings from a international team of specialists, and will continue to inspire and extend practical applications of size ...